Determination of JNK and Akt activities with and without LY294002 (LY) after 4 h of reperfusion after ischemia and effect of LY on the level and activity of MKP-7 after 4 h of reperfusion.A. Effect of LY on Akt and JNK activities after 4 h of reperfusion. B. Effect of LY treatment on MKP-7 level after 4 h of reperfusion. C. Effect of LY treatment on MKP-7 activity after 4 h of reperfusion. ODs are presented as means ± SEMs (n = 4) and expressed as magnitudes of change versus sham control. *P < 0.05, versus sham control, # P < 0.05, comparison between chemically treated 4-h reperfusion groups and their vehicle control.
Zhu et al. BMC Neuroscience 2013 14:1 doi:10.1186/1471-2202-14-1