Erythropoietin-treated mice exposed to IH do not exhibit deficits in learning and memory functions. (A and B) Mean latencies (s) and pathlengths (cm) to locate the target platform during place training in mice either exposed to intermittent hypoxia (IH) or maintained in room air (RA) (n = 24 per group; * - p < 0.001), and receiving either vehicle (C) or EPO. (C) Swim Speed (D) Mean percentage time in the target quadrant during probe trial after completion of water maze testing (n = 24/experimental group;* -p < 0.001).
Dayyat et al. BMC Neuroscience 2012 13:77 doi:10.1186/1471-2202-13-77