Clusters of significant correlations between age and strength of inflow projected on a template brain. Positive t-values (cluster 1-4 jointly illustrated) indicate that older people have more inflow in this region (mainly medial temporal lobes including hippocampus); negative t- values (cluster 5) imply less inflow for older adults. A cluster-based randomization was done in order to calculated the t-values from a distribution of 1000 randomizations.
Schlee et al. BMC Neuroscience 2012 13:16 doi:10.1186/1471-2202-13-16