Table 2 |
|||
| Comparison of physiological changes between the UNICAR and BICAR groups | |||
| UNICAR | BICAR | P-value† | |
| (n = 8) | (n = 9) | ||
| Pre-MCAO | |||
| Hgb (g/dl) | 14.09 ± 1.03 | 13.62 ± 0.96 | 0.351 |
| pH | 7.37 ± 0.04 | 7.35 ± 0.04 | 0.252 |
| pCO2 (mmHg) | 43.38 ± 3.98 | 46.53 ± 4.51 | 0.149 |
| pO2 (mmHg) | 87.28 ± 6.07 | 89.00 ± 5.17 | 0.536 |
| K+ (mmol/L) | 3.86 ± 0.62 | 4.03 ± 0.39 | 0.499 |
| Na+ (mmol/L) | 140.24 ± 2.64 | 121.17 ± 43.80 | 0.228 |
| Cl- (mmol/L) | 104.33 ± 3.66 | 101.62 ± 3.22 | 0.126 |
| Glucose (mg/L) | 139.75 ± 10.59 | 133.78 ± 6.50 | 0.176 |
| MABP (mmHg) | 86.25 ± 10.65 | 82.00 ± 6.48 | 0.330 |
| MCAO 30’ | |||
| Hgb (g/dl) | 13.99 ± 1.50 | 13.00 ± 1.48 | 0.193 |
| pH | 7.36 ± 0.03 | 7.35 ± 0.04 | 0.653 |
| pCO2 (mmHg) | 45.45 ± 5.49 | 47.74 ± 8.63 | 0.529 |
| pO2 (mmHg) | 83.33 ± 10.56 | 85.89 ± 3.47 | 0.529 |
| K+ (mmol/L) | 3.94 ± 0.43 | 4.10 ± 0.34 | 0.384 |
| Na+ (mmol/L) | 138.60 ± 2.84 | 135.78 ± 3.10 | 0.071 |
| Cl- (mmol/L) | 106.39 ± 4.03 | 104.13 ± 3.65 | 0.245 |
| Glucose (mg/L) | 134.50 ± 11.20 | 132.56 ± 5.05 | 0.662 |
| MABP (mmHg) | 87.75 ± 7.78 | 81.78 ± 6.76 | 0.111 |
| Rep 30’ | |||
| Hgb (g/dl) | 12.84 ± 1.37 | 12.82 ± 1.29 | 0.981 |
| pH | 7.36 ± 0.03 | 7.33 ± 0.04 | 0.117 |
| pCO2 (mmHg) | 42.46 ± 8.58 | 44.34 ± 5.85 | 0.601 |
| pO2 (mmHg) | 96.36 ± 14.10 | 88.84 ± 6.17 | 0.195 |
| K+ (mmol/L) | 3.86 ± 0.57 | 3.79 ± 0.42 | 0.793 |
| Na+ (mmol/L) | 139.23 ± 2.53 | 136.41 ± 3.83 | 0.099 |
| Cl- (mmol/L) | 106.00 ± 3.25 | 104.56 ± 4.36 | 0.456 |
| Glucose (mg/L) | 142.13 ± 17.69 | 133.56 ± 5.75 | 0.225 |
| MABP (mmHg) | 86.00 ± 10.89 | 81.11 ± 4.94 | 0.271 |
Data are presented as mean ± standard deviation.
Pre-MCAO: before MCAO; MCAO 30’: at 30 min after MCAO; Rep 30’: at 30 min after reperfusion. UNICAR, unilateral carotid artery reperfusion; BICAR, bilateral carotid artery reperfusion; Hgb, hemoglobin; MCAO, middle cerebral artery occlusion; MABP, mean arterial blood pressure.
† determined by independent t-test.
Liu et al. BMC Neuroscience 2012 13:154 doi:10.1186/1471-2202-13-154