Comparison of current activation threshold of the Aβ-fiber neurons in response to stimulation of the dorsal roots, between control and neuropathic rats. Dorsal root current threshold was defined by the chronaxie curve (threshold-duration), which was determined as the minimum stimulus current to the dorsal root sufficient to evoke a soma AP with pulses of 0.1 ms, 1 ms, 2 ms, 4 ms and 6 ms duration. Figures show a reduction in the rheobase in DRG neurons in neuropathic animals. Details of abbreviations are as indicated in Figures 2 and 4.
Zhu and Henry BMC Neuroscience 2012 13:15 doi:10.1186/1471-2202-13-15