Figure 4.

Comparison of the activation threshold of Aβ-fiber neurons in response to intracellular current injection, between control and neuropathic (NeP) rats. The current threshold was defined as the minimum current required to evoke an AP by intracellular current injection. Excitability of the DRG somata was significantly increased, as indicated by the decreased activation threshold in MS and HTM neurons. CUT, cutaneous neurons, include Aβ-fiber LTM GF, RA, and SA neurons. Asterisks above the graph indicate the significant difference between control and neuropathic animals: *p < 0.05. Unpaired t-test.