Hierarchical cluster analysis of the factor loading scores from 40 demographic, medical, neuropsychological, neuroimaging, and gene expression variables that distinguish subjects with alcohol use disorders from healthy controls. Note the trends for significantly changed neuropsychological variables to load most heavily on factor 1, significantly changed genes to load on factor 2, drinking variables to load on factor 3, and neuroimaging variables to load on factors 4 and 5. One exception to this is the left hemisphere parietal inferior supramarginal gyrus, which showed a strong relationship to the significantly changed gene cluster.
Hicks et al. BMC Neuroscience 2012 13:128 doi:10.1186/1471-2202-13-128