Neurological scores (A) and infarct volumes (B, C) at 72 h after reperfusion in the rats. Pretreatment with EA significantly improved the neurological scores and reduced the infarct volume while the γ-secretase inhibitor MW167 abolished the protective effect of EA pretreatment. Treatment with MW167 in MCAO only animals also induced neuroprotective effect. (*P < 0.05 vs. CON; #P < 0.05 vs. MW167).
Zhao et al. BMC Neuroscience 2012 13:111 doi:10.1186/1471-2202-13-111