Effect of GSPE on 0.1 mM [Mg2+]o and oxygen glucose deprivation-induced neurotoxicity. A: Hippocampal neurons were exposed to normal medium or 0.1 mM [Mg2+]o-containing medium with or without GSPE (6 μg/ml, n = 8) for 20-24 h. B: Hippocampal neurons were exposed to normal or oxygen glucose deprived conditions without GSPE (OGD, n = 8) or with GSPE (6 μg/ml, n = 8) for 90 min. After 20-24 h, the same fields of cells were recounted. Data are expressed as the mean ± SEM. *P < 0.001 relative to the control, # P < 0.05 relative to 0.1 mM [Mg2+]o or OGD (ANOVA with Bonferroni's test).
Ahn et al. BMC Neuroscience 2011 12:78 doi:10.1186/1471-2202-12-78