Experimental model. Surgical implantation of a collagen/PCL nerve conduit (collagen/PCL NC) bridging an 8 mm sciatic nerve defect in rats (A) and the view of the regenerated nerve 4 months postoperatively (B). Electrospun artificial nerve conduit implanted in rats after 4 months was surrounded by a thin layer of fibrous connective tissue with abundant capillaries. The original boundary areas between conduit and nerve (black arrows) became blurry and the conduit degraded gradually as regenerated nerve went through.
Yu et al. BMC Neuroscience 2011 12:68 doi:10.1186/1471-2202-12-68