Neurotrophic factors effected by CART. RT-PCR was performed to calculate the endogenous expression of BDNF and NGF in Day 3 and Day 6. In contrast with the control group, the amount of BDNF was 1.68-fold and 2.45-fold higher with the incubation of CART at 3 days and 6 days. NGF was also higher with incubation of cart, with 1.05-fold of the control group in Day 3 and 2.01-fold of the control group in Day 6. There were no significant differences between CART treated-group and growth factor treated-group. (* p < 0.05 versus control group).
Liu et al. BMC Neuroscience 2011 12:67 doi:10.1186/1471-2202-12-67