Effects of learning on MUA firing rates and synchronization. (A) mean ± sem change in firing rate in response to visual discrimination stimuli in recording channels showing an overall increase in firing rate during the stimulus across a blocks of trials where either the animals (Sheep A-C and either left or right IT) were still learning (NL = not learned) or had learned (> 80% correct choice, L = learned)(open bars are pre-stimulus and black bars during stimulus values). The overall mean for all animals is shown on the right hand side of each set of histograms. (B) Similar changes in firing rates of recording channels showing reduced firing rates. (C) Change in synchronization index of neuronal firing as a function of learning. Paired t-test: * p < 0.05, ** p < 0.01 for the 500 ms pre vs 500 ms during the stimulus. (D) Shows overall % changes across the 3 animals as a function of learning with significant effects of learning revealed by ANOVA tests only for the synchronization index in both left and right IT (## p < 0.01).
Kendrick et al. BMC Neuroscience 2011 12:55 doi:10.1186/1471-2202-12-55