Figure 3.

Upregulated p21 and p27 expression in adult mouse NSCs treated with HDACi is associated with increased acetylation at the proximal promoter. (a) Chromatin immunoprecipitation (ChIP) reveals significant increases in histone H3 lysine 9 acetylation levels at the proximal promoter of p21 in SAHA (***p < 0.001) and NaB (*p < 0.05) treated adult mouse NSCs. (b) ChIP reveals significant increases in histone H3 lysine 9 acetylation levels at the proximal promoter of p27 in SAHA (**p < 0.01) but not NaB treated adult mouse NSCs. Statistical comparisons performed using two-way ANOVA with Bonferroni post-tests.

Zhou et al. BMC Neuroscience 2011 12:50   doi:10.1186/1471-2202-12-50
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