Figure 4.

Vestibular dysmorphism in caspase-3 deficient mice. Temporal bones of Casp3-/-, Casp3+/- and Casp3+/+ mice at postnatal day 20. Truncation of the left superior semicircular canal in a Casp3-/- mouse is shown (arrow). Most Casp3-/- (n = 14) had variable degrees of dysmorphisms in the anterior semicircular canal, whereas all Casp3+/- (n = 20) and Casp3+/+ (n = 14) had normal inner ear morphology. ant, anterior semicircular canal. lat, lateral semicircular canal. post, posterior semicircular canal. cc, common crus. Scale bar, 1mm.

Makishima et al. BMC Neuroscience 2011 12:102   doi:10.1186/1471-2202-12-102
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