Glutamatergic effects on feeding and water consumption plus on overall behavioral activity during hibernation. The influences of the same treatment modality reported in Figure 1 were assessed on (A) water (ml) and (B) food (g) consumption of hamsters for the entire 8 days hibernating session with the first day prior to it being considered as a negative control. These effects were also compared to (C) overall motor behavior of the hamster, this time during a 4 h interval prior to arousal. At the same time the role of CPP (black square) and CNQX (white square) on total water consumption with respect to controls (white circle) were compared during the latter part of this physiological state and precisely the last four days of hibernation (Figure 3A'). The variations induced by both CPP- and CNQX-treated animals were compared in the same manner to that used in Figure 2.
Alò et al. BMC Neuroscience 2011 12:10 doi:10.1186/1471-2202-12-10