Micrographs of hematoxylin and eosin staining (×400). (A) The micrographs from an animal with Tarlov score 4 in sham group showed no histopathology abnormity. (B) The image from an animal with Tarlov score 0 in I/R group. The arrows indicate ischemia neuron cells showing intensely eosinophilic cytoplasm, Nissl body loss, and pyknosis. The arrow heads indicate pronounced vacuolization in the anterior horn. (C) The micrographs from an animal with Tarlov score 2 in HSYA-treatment group revealed alleviated destruction after HSYA treatment. (D) The number of normal motor neurons in the anterior horn 48 h after reperfusion. * P < 0.05 versus sham group; # P < 0.05 versus I/R group.
Shan et al. BMC Neuroscience 2010 11:98 doi:10.1186/1471-2202-11-98