Additional file 1.

Curcumin alters αS aggregation kinetics. Aggregation kinetics were monitored using Thioflavin T assay. (A) monomeric αS and monomeric αS + curcumin, (B) pre-formed oligomeric αS and pre-formed oligomeric αS + curcumin, (C) pre-formed fibrillar αS and pre-formed fibrillar αS + curcumin. Samples were taken at the indicated time and mixed with Thioflavin T. The observed Thioflavin T fluorescence (Ex = 450 nm, Em = 482 nm) was normalized to each untreated αS sample at its maximum value. Data are presented as mean ± SE from 4 sets of experiments.

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Wang et al. BMC Neuroscience 2010 11:57   doi:10.1186/1471-2202-11-57