Curcumin ameliorates αS-induced morphological changes in SH-SY5Y cells evaluated by fluorescence microscopy. After 48 hr incubation, cells were fixed with 4% paraformaldehyde, stained with Hoechst 33342 (5 mg/mL) and analyzed using a Nikon TE300 fluorescence microscope. Fluorescence micrographs (100× magnification) of the (A) control cells, (B) cells exposed to αS, (C) cells exposed to αS+curcumin and (D) curcumin.
Wang et al. BMC Neuroscience 2010 11:57 doi:10.1186/1471-2202-11-57