Pantethine treatment preserves striatal dopamine levels and motor activity. (A), striatal levels of dopamine (DA) and its derivatives DOPAC and HVA. (B), motor function evaluated in the pole test (TLA, motor activity time, indicates the time for the mice to go back to the ground). Values are means ± SEM, n = 10 mice per group. MPTP refers to 2'-methyl-MPTP. Significant difference between saline and pantethine-treated groups, *p < 0.05; **p < 0.01.
Cornille et al. BMC Neuroscience 2010 11:51 doi:10.1186/1471-2202-11-51