Activity-driven collapse (A and B) of two types of projections (EphA3+ and EphA3-) is different from noise-driven collapse (C and D) (Eact = 0). (A and C) The axonal positions in the target are shown as a function of the position of their origin in retina. Individual EphA3+/EphA3- axons are represented by blue/cyan points. (B and D) The distribution of terminal positions in the target for subset of axons originating from different retinal locations marked 1-3 in A and C. (B) includes projections for a single instance of mapping. (D) includes sum of projections for 1500 maps, which is necessary due to the degree of noise in the absence of correlated activity.
Tsigankov and Koulakov BMC Neuroscience 2010 11:155 doi:10.1186/1471-2202-11-155