Table 1

Animal and Experimental Group Assignments

Animal Group

N

Label

Injury

Type

Survival Time Post-injury

Total Survival Post-Labelling

Group Comparisons


1

4

FG

No

---

---

7 days

1 to 4

2

4

FG

No

---

---

2 weeks

1 to 5

3

4

FG

No

---

---

1 month

2 to 6

4

4

FG

Yes

Txn

3 days

10 days

3 to 7

5

4

FG

Yes

Txn

1 week

2 weeks

8 to 9

6

4

FG

Yes

Txn

2 weeks

3 weeks

7

4

FG

Yes

Txn

1 month

5 weeks

8

4

DTMR

No

---

---

2 weeks

9

4

DTMR

Yes

Con

1 week

2 weeks


Animal Group Assignments. Female Long-Evans rat were divided among 9 groups. Using the indicated tracer, Fluorogold (FG) or Dextran Tetramethyl Rhodamine (DTMR), TPS neurons were prelabelled by a series of bilateral injections into the upper lumbrosacral enlargement. Allowing 1-week for tracer transport, animals in groups 4-8 were subjected to either a T9 complete spinal transection (Txn) or moderate spinal contusion injury (25 mm weight drop, NYU Impactor; Con). Following spinal cord injury, animals were allowed to recover for the indicated period of time. The final column of this table indicates the time point comparisons that were made for both the gene and PCR validation studies conducted during this study

Siebert et al. BMC Neuroscience 2010 11:148   doi:10.1186/1471-2202-11-148

Open Data