Email updates

Keep up to date with the latest news and content from BMC Neuroscience and BioMed Central.

Open Access Highly Accessed Research article

The p75 neurotrophin receptor is expressed by adult mouse dentate progenitor cells and regulates neuronal and non-neuronal cell genesis

Ramon O Bernabeu12 and Frank M Longo3*

Author Affiliations

1 Department of Neurology, UCSF/VAMC, San Francisco, CA, 94121, USA

2 Institute of Cell Biology and Department of Physiology, University of Buenos Aires, Buenos Aires, Argentina

3 Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA, 94035, USA

For all author emails, please log on.

BMC Neuroscience 2010, 11:136  doi:10.1186/1471-2202-11-136

Published: 20 October 2010

Additional files

Additional file 1:

Confocal 3D reconstructed imaging of p75NTR expression in BrdU-positive granular cells. Dentate gyrus coronal sections harvested from three p75NTR +/+ mice were co-immunostained with antibodies against p75NTR (green) and BrdU (red). A representative confocal 3D-reconstructed, merged image of a SGZ cell demonstrates nuclear BrdU signal with p75NTR signal evident in cytoplasmic and nuclear areas. Orthogonal images demonstrate x - z (top) and y - z (right) planes. Scale bar: 5 μm.

Format: TIFF Size: 1MB Download file

Open Data