BMC Neuroscience

official impact factor 3.09

This article is part of the supplement: Eighteenth Annual Computational Neuroscience Meeting: CNS*2009

Open Access Poster presentation

A model for simultaneous encoding of "where" and "what" information in prefrontal cortex

Efrat Barak-Shimron1*, Ron Meir2 and Yehoshua Y Zeevi2

Author Affiliations

1 Department of Medicine, Technion – Israel Institute of Technology, Haifa, 32000, Israel

2 Department of Electrical Engineering, Technion – Israel Institute of Technology, Haifa, 32000, Israel

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BMC Neuroscience 2009, 10(Suppl 1):P283 doi:10.1186/1471-2202-10-S1-P283

Published: 13 July 2009

First paragraph (this article has no abstract)

In contrast to the classical theory of segregated cortical representation of information regarding the identity ("what") and location ("where") of a visual object, recent experimental results indicate that neurons in the primate prefrontal cortex convey combined information about both [1]. Moreover, this information was found to be maintained after stimulus removal, suggesting that these neurons contribute to working memory. To date, the mechanisms that underlie this integrated representation are unknown. In this study, we propose a model of a cortical network with biologically realistic properties that demonstrates a combined representation of stimulus identity and location.