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This article is part of the supplement: Eighteenth Annual Computational Neuroscience Meeting: CNS*2009

Open Access Poster presentation

Temporal structure of bursting patterns as representation of input history

Bóris Marin1*, Fabiano Baroni2, Pablo Varona2 and Reynaldo D Pinto3

Author Affiliations

1 Instituto de Física, Universidade de São Paulo, 05508-090 SP, Brazil

2 Escuela Politécnica Superior, Universidad Autónoma de Madrid, 28049, Spain

3 Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos 13560-970 SP, Brazil

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BMC Neuroscience 2009, 10(Suppl 1):P101  doi:10.1186/1471-2202-10-S1-P101


The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1471-2202/10/S1/P101


Published:13 July 2009

© 2009 Marin et al; licensee BioMed Central Ltd.

Poster presentation

Single neurons exhibit complex dynamical repertoires, where interacting dynamics on many different time scales enable history-dependent forms of computation [1]. We investigate these phenomena in a biophysically realistic conductance-based model (similar to the one presented in [2]) of a bursting neuron from a crustacean Central Pattern Generator. The analysis is focused on the temporal structure of the bursting phase, describing how temporal patterns of spikes within bursts convey information about the previous history of stimulation to the cell. An electrophysiological mechanism for these behaviors is proposed, inferred from the geometrical structure of the system's phase space. We discuss the relevance of the phenomenon for homeostatic self-regulation of rhythmic activity in Central Pattern Generators, and as a possible communication mechanism between the CPG and higher centers in the nervous system. We are considering several experimental protocols to validate our theoretical work.

Acknowledgements

This work is supported by Brazilian agencies Fapesp and CAPES, CNPq, and Spanish grants MEC PHB2007-0013TA, BFU2006-07902/BFI, TIN 2007-65989 and CAM S-SEM-0255-2006.

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