Development of neuronal activity of nSFEB, SNP or MNP cultures. Overview (a; b; c; upper panel) and detailed (a; b; c; lower panel) phase-contrast images of different cultures on MEAs in the presence (+FGF2) and after the removal (-FGF2) of FGF2. White-labeled electrodes represent electrodes that detect spontaneous spikes and black-labeled electrodes detect no spikes. White boxes in upper panels indicate regions which are presented at higher magnification in the lower panels. Electrode diameter = 30 μm.
Illes et al. BMC Neuroscience 2009 10:93 doi:10.1186/1471-2202-10-93