Table 1

Levels of MMP-9 and TIMP-1 protein in the middle cerebral artery after MCAO and after treatment with the MEK1/2 inhibitor U0126 at 0, 6, and 12 hours post occlusion

Middle cerebral artery


Control

MCAO

MCAO + U0126 - 0 h

MCAO + U0126 - 6 h

MCAO + U0126 - 12 h

MMP-9 (%) ± SEM

100 ± 3

198 ± 7**

114 ± 10§

113 ± 8§

144 ± 5

TIMP-1 (%) ± SEM

100 ± 5

191 ± 7**

137 ± 5

100 ± 4§§

184 ± 19


Maddahi et al. BMC Neuroscience 2009 10:56   doi:10.1186/1471-2202-10-56

Open Data