Figure 4.

Response of the model to negative feedback of cortisol regulation from a) the hypothalamus and b) pituitary c) increased CRH and d) decreased CRH production. Parameters were changed by a factor of 10–50% inducing changes in circulating cortisol levels as described in accompanying tables, modelled using SBML as detailed in the methods section.

McAuley et al. BMC Neuroscience 2009 10:26   doi:10.1186/1471-2202-10-26
Download authors' original image