Subcellular localization of PGRN within motor neurons in primary cultures relative to markers for the ER, Golgi apparatus and chromogranin-A containing vesicles. Immunolabelling of motor neurons in dissociated spinal cord-DRG cultures with anti-Calreticulin (a), anti-GM130 (b), Chromogranin A (c) and anti-PGRN (middle column). Confocal images were captured at 63× magnification, hatched boxes represent 3-5× zoom.
Ryan et al. BMC Neuroscience 2009 10:130 doi:10.1186/1471-2202-10-130