PGRN expression within the dissociated spinal cord-DRG cultures. Confocal Images taken of dissociated spinal cord cultures. PGRN (red) is very clearly expressed within motor neurons (a), labelled with SMI32 (green). PGRN is also expressed by microglia, as demonstrated by colocalization between PGRN and CD11b (c). Astrocytes, however, do not express PGRN, as demonstrated in (b).
Ryan et al. BMC Neuroscience 2009 10:130 doi:10.1186/1471-2202-10-130