Figure 5.

Nuclear extracts from the hypermutating B cell line, Ramos, support faithful repair of U•G mispairs. (A) Schematic of M13-Gap51 substrates, which carry a 51 nt gap in the lacZα region of M13mp18. (B) Efficiency of repair of M13-Gap51 or M13-U•G substrates, determined by quantitating the fraction of clear and pale blue plaques on X-gal indicator plates. P values were determined by two-tailed Fisher's exact test.