Table 4 |
||||||
|
Details of candidate endogenous control (EC) genes and their PCR amplification efficiencies |
||||||
|
Name |
Mature length (nt) |
RNA species |
Accession number |
Function |
Reference |
PCR Amplification efficiency (%) |
|
|
||||||
|
let-7a |
22 |
miRNA |
MI0000060* |
Negatively regulates RAS oncogene |
[57] |
96.3 |
|
miR-10b |
22 |
miRNA |
MI0000267 * |
No functionally-verified targets |
104.1 |
|
|
miR-16 |
22 |
miRNA |
MI0000070 * |
Negatively regulates B-cell lymphoma mRNA in chronic lymphocytic leukaemia patients |
[7] |
104.3 |
|
miR-21 |
22 |
miRNA |
MI0000077 * |
Antiapoptotic, negatively regulates apoptosis-related genes |
[42] |
96.8 |
|
miR-26b |
22 |
miRNA |
MI0000084 * |
No functionally-verified targets |
98.1 |
|
|
RNU19 |
198 |
snoRNA |
X94290 ** |
May be involved in pre-rRNA processing |
99.2 |
|
|
RNU48 |
63 |
snoRNA |
NR_002745 ** |
Guides the 2'O-ribose methylation of 28S rRNA |
[62] |
108.9 |
|
Z30 |
97 |
snoRNA |
AJ007733 ** |
Guides the methylation of the Am47 residue in U6 snRNA |
[63] |
104.1 |
|
|
||||||
|
*mirBase database accession number ** Entrez gene ID |
||||||
|
Davoren et al. BMC Molecular Biology 2008 9:76 doi:10.1186/1471-2199-9-76 |
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