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Body weights and plasma values of the four groups of rats under study |
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| Control |
1,25D3 |
STZ |
STZ + 1,25D3 |
|
|
|
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| Final weight (g) |
283 ± 1 |
290 ± 2a |
242 ± 6ab |
254 ± 3abc |
| Glucose (mg/dl) |
125 ± 7 |
130 ± 2 |
420 ± 36ab |
459 ± 16ab |
| Insulin (ng/ml) |
1.6 ± 0.3 |
1.5 ± 0.2 |
0.7 ± 0.3ab |
0.5 ± 0.1ab |
| 25-Hydroxy-vitamin D3 (ng/ml) |
19 ± 1 |
15 ± 1 |
15 ± 3 |
17 ± 3 |
| Calcium (mg/dl) |
7.5 ± 1 |
10 ± 1 |
10 ± 0.4 |
11 ± 1a |
| Phosphorus (mg/dl) |
6.8 ± 1 |
8.7 ± 1 |
7.2 ± 0.5 |
11 ± 0.7ac |
| Proteins (mg/dl) |
65 ± 1 |
66 ± 1 |
63 ± 0.9 |
64 ± 1 |
|
Sham-treated rats (Control), rats treated with 1,25D3 [150 IU/Kg (3.75 μg/Kg) one a day, for 15 days] (1,25D3), streptozotocin-induced diabetic rats (STZ) and streptozotocin-induced diabetic rats treated with 1,25D3 (STZ+1,25D3). Values are the mean ± SEM of 6–12 determinations in each group. a p < 0.05 vs. Control-rats; b p < 0.05 vs. 1,25D3-rats; c p < 0.05 vs. STZ-rats. | ||||
Calle et al. BMC Molecular Biology 2008 9:65 doi:10.1186/1471-2199-9-65 |
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