A GATA4/WT1 cooperation regulates transcription of genes required for mammalian sex determination and differentiation

Yoko Miyamoto^*¹ , Hiroaki Taniguchi^*¹ , Frédéric Hamel¹ , David W Silversides³ and Robert S Viger¹^,2

¹Ontogeny-Reproduction Research Unit, Centre de Recherche du Centre Hospitalier Universitaire de Quebec (CRCHUQ), Quebec City, QC, G1V 4G2, Canada

²Centre de Recherche en Biologie de la Reproduction (CRBR) and Department of Obstetrics and Gynecology, Laval University, Quebec City, QC, G1K 7P4, Canada

³Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, J2S 7C6, Canada

author email corresponding author email* Contributed equally

BMC Molecular Biology 2008, 9:44doi:10.1186/1471-2199-9-44


Published:	29 April 2008

Additional files

Additional file 1:

Species conservation of the consensus GATA and WT1 binding sites in the proximal AMH promoter.

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Additional file 2:

Expression of the renilla luciferase (phRL-TK) control plasmid is not significantly affected by GATA4 and/or WT1 overexpression in HeLa cells.

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