Table 1

List of transcripts upregulated by 16 h-leptin treatment in RINm5F cells





Signal intensities








Gene symbol*
GenBank Accession.
UniGene
mock
leptin
Fold induction by leptin

Phosphatidate phosphohydrolase 2a
Ppap2a
AI555126
Rn.61687
0.3
2.4
8.9
Regulator of G-protein signaling 4
Rgs4
AI502324
Rn.11065
3.2
16.9
5.2
Preprotachykinin 1
Tac1
AA818532
Rn.1920
44.6
188.2
4.2
Fibrinogen, beta polypeptide
Fgb
AI059690§
Rn.11416
3.0
11.4
3.8§
Plasminogen activator, tissue-type (tPA)
Plat
AA875008
Rn.107102
2.3
7.7
3.3
Lipocalin 2
Lcn2
AI137617
Rn.11303
2.7
8.7
3.2
Pancreatitis-associated protein (PAP1)
Pap
AA998280
Rn.9727
1.9
5.5
2.9
superoxide dismutase 2 (MnSOD)
Sod2
AI029806
Rn.10488
17.1
48.3
2.8

* Official gene symbol in the Rat Genome Database

Phosphoimager evaluation of filter array hybridization (relative units corrected to background and normalized to β actin

Representative of four different Rgs4 cDNA clones (ratios: 5.2, 2.9, 2.8 and 2.4).

§ Representative of two different fibrinogen-β cDNA clones (ratios: 3.8 and 2.8).

Hekerman et al. BMC Molecular Biology 2007 8:41   doi:10.1186/1471-2199-8-41