Table 3

Overall comparison of the four RNA extraction protocols for quantity (in pg/μl) and quality (RIN) for ten year old FFPE samples.

Ten year old samples:

Protocol 1
Protocol 2
Protocol 3
Protocol 4

FFPE tissue input

80 μm
10 μm
20 μm
50 μm
Successful extractions

36/42 (86%)
26/42 (62%)
38/42 (90%)
30/42 (71%)
RNA (pg/μl)
Minimum value
975
1,650
1,314
9864

Maximum value
73,861
165,588
137,594
314,693

Mean
15,964
51,985
29,661
107,042

Median
8,750
31,104
19,458
86,682
RIN
Minimum value
1.0
1.5
1.0
1.8

Maximum value
2.5
5.2
4.4
6.1

Mean
1.8
2.5
2.3
2.4

Median
2.0
2.3
2.2
2.2

Ribeiro-Silva et al. BMC Molecular Biology 2007 8:118   doi:10.1186/1471-2199-8-118