Figure 6.

Induction of COX-2 promoter activity by NF-κB subunits. Expression vectors for the NF-κB subunits p50 and p65 were cotransfected with the COX-2 promoter in HeLa cells. Both subunits can activate COX-2 promoter activity. Standard deviations of triplicate transfection assays are depicted as arrow bars. Fold induction was normalized to control, that is the COX-2 promoter reporter vector alone (1 fold induction).