Expression ratios of other cancer-related genes normalized to PPIA and RPS13 housekeeping genes. Boxes represent the lower and upper quartiles with medians in the 16 tumor samples compared to paired normal tissues (set at 1, red dot line); whiskers indicate the Tukey confidence intervals and black dots (•) are outlier values. VEGFa, c-Myc, CycD1 and megalin are significantly overexpressed in tumors (***p < 0.001, **p < 0.01, *p < 0.05, Wilcoxon Test) in comparison to PCNA and YBX3, which are globally not different from paired normal tissues. Beta-Actin expression is variable in tumor samples with a tendency to be down-regulated. (Please note the logarithmic Y axis due to strong c-Myc and Megalin overexpression).
Dupasquier et al. BMC Molecular Biology 2014 15:9 doi:10.1186/1471-2199-15-9