Effects on the MTG16 promoter activity of GATA-1 overexpression. MEG-01 cells were co-transfected with 15 μg MTG16 -668 to -57 bp promoter plasmid and increasing amounts of GATA-1 plasmid. The luciferase activity is normalized against Renilla and the activity of the MTG16 -668 to -57 bp promoter. The MTG16 promoter is activated by GATA-1 overexpression. The data are from 3 separate experiments. Bars represent the mean and the error bars show SEM. Statistically significant differences are marked by star.
Ajore et al. BMC Molecular Biology 2012 13:11 doi:10.1186/1471-2199-13-11