Combined ChIP-MeDIP analysis at a single locus is sufficient to demarcate normal cervical tissues from cervical cancer. 5mC data for five normal and five cancer samples is compared (Figure 4) to either 5mC/Pol II or 5mC/H3K27m3 ratio. The red horizontal line demarcates the highest value for the normal tissues.
Yu et al. BMC Molecular Biology 2011 12:49 doi:10.1186/1471-2199-12-49