Phospholipase A2 of B. flaviceps venom gland cDNA library. Similar sequences were clustered together and a representative of the each cluster is presented. B. flaviceps PLA2s can be divided into two distinct groups (A and B). The deduced amino acid sequences of isoforms of each group are shown. The amino residues which are different from the representative major isoform are shaded. The predicted signal peptide of the transcripts is shown in bold and the propeptide is underlined. The major isoforms from each group is aligned with closely related protein found in the database and the % identity and similarly are also shown in the figure. A) Putative PLA2 precursors of B. flaviceps and alignment with PA22_BUNFL (Q7T2Q4.1) from B. flaviceps. B) Putative β-bungarotoxin chain A of B. flaviceps and alignment with PA2A2_BUNFL (Q7T1R1.1) from B. flaviceps. The extra cysteine residue involved in formation of disulphide bridge with chain A of β-bungarotoxin is underlined.
Siang et al. BMC Molecular Biology 2010 11:24 doi:10.1186/1471-2199-11-24