Evidence of a tick RNAi pathway by comparative genomics and reverse genetics screen of targets with known loss-of-function phenotypes in Drosophila
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* Corresponding author: Ala E Lew-Tabor ala.lew@dpi.qld.gov.au
- † Equal contributors
BMC Molecular Biology 2009, 10:26 doi:10.1186/1471-2199-10-26
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Research article
Katherine M Kocan, Zorica Zivkovic, Edmour F Blouin, Victoria Naranjo, Consuelo Almazán, Ruchira Mitra, José de la Fuente BMC Developmental Biology 2009, 9:42 (16 July 2009) When four tick host genes, whose expression is altered by the cattle pathogen Anaplasma marginale, are silenced by RNA interference, no salivary gland infections are seen in the gene-silenced insects, suggesting a role in the pathogen life-cycle in ticks.
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