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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Damian Marlee
Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of transcription, mRNA processing, translation, replication, recombination, mutation, and repair.
BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Scientific (ISI) and Google Scholar.
BMC Molecular Biology 2008, 9 :21
Diverse proteins are generated from a single arthropod myosin heavy chain gene, according to clues provided by comparative genomic analysis, by first splicing the mutually exclusive exons and only then splicing the introns.
BMC Molecular Biology 2007, 8 :115
Desert Massasauga rattlesnake venom is composed of a wide range of toxin proteins, some unexpectedly shared with snakes outside the viper family, and one potential new toxin arising from the fusion of two known toxin genes.
BMC Molecular Biology 2007, 8 :109
Exonization of transposed elements is higher within duplicated genes, implying that duplicates of the transcription initiation factor gene TIF-1A, for example, are free from the evolutionary constraints on single-copy genes.
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Research article
Identification of valid reference genes for the normalization of RT qPCR gene expression data in human brain tissue. David T R Coulson, Simon Brockbank, Joseph G Quinn, Suzanne Murphy, Rivka Ravid, G BRENT Irvine, Janet A Johnston BMC Molecular Biology 2008, 9 :46 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Characterization of two functional NKX3.1 binding sites upstream of the PCAN1 gene that are involved in the positive regulation of PCAN1 gene transcription
Wenwen Liu, Pengju Zhang, Weiwen Chen, Chunxiao Yu, Fuai Cui, Feng Kong, Jianye Zhang, Anli Jiang BMC Molecular Biology 2008, 9 :45 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
A GATA4/WT1 cooperation regulates transcription of genes required for mammalian sex determination and differentiation Yoko Miyamoto, Hiroaki Taniguchi, Frederic Hamel, David W Silversides, Robert S Viger BMC Molecular Biology 2008, 9 :44 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Molecular characterization of senescence marker protein-30 gene promoter: Identification of repressor elements and functional nuclear factor binding sites Bandita Rath, Ravi S Pandey, Priya R Debata, Naoki Maruyama, Prakash C Supakar Sr BMC Molecular Biology 2008, 9 :43 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Mutation detection using ENDO1: application to disease diagnostics in humans and TILLING and Eco-TILLING in plants Karine Triques, Elodie Piednoir, Marion Dalmais, Julien Schmidt, Christine Le Signor, Mark Sharkey, Michel Caboche, Benedicte Sturbois, Abdelhafid Bendahmane BMC Molecular Biology 2008, 9 :42 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK Sonja Langmesser, Tiziano Tallone, Alain Bordon, Sandro Rusconi, Urs Albrecht BMC Molecular Biology 2008, 9 :41 (22 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
DNA watermarks: A proof of concept Dominik Heider, Angelika Barnekow BMC Molecular Biology 2008, 9 :40 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
DNA demethylation-dependent enhancement of toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription Takashi Furuta, Tsuyoshi Shuto, Shogo Shimasaki, Yuko Ohira, Mary Ann Suico, Dieter C Gruenert, Hirofumi Kai BMC Molecular Biology 2008, 9 :39 (21 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The calcium channel Alicia M Ebert, Catherine A McAnelly, Ashok Srinivasan, Rachel Lockridge Mueller, David B Garrity, Deborah M Garrity BMC Molecular Biology 2008, 9 :38 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Gene transfer of Hodgkin cell lines via multivalent anti-CD30 scFv displaying bacteriophage Yoon-Suk A Chung, Katja Sabel, Martin Kr BMC Molecular Biology 2008, 9 :37 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Microsatellite evolution: Mutations, sequence variation, and homoplasy in the hypervariable avian microsatellite locus HrU10 Jarl A Anmarkrud, Oddmund Kleven, Lutz Bachmann, Jan T Lifjeld BMC Evolutionary Biology 2008, 8 :138 (9 [Abstract ] [Provisional PDF ]
Research article
Sequence Diversity in the A Domain of Staphylococcus aureus Fibronectin-Binding Protein A Anthony Loughman, Tara Sweeney, Fiona M Keane, Giampiero Pietrocola, Pietro Speziale, Timothy J Foster BMC Microbiology 2008, 8 :74 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Inferring the role of transcription factors in regulatory networks Philippe Veber, Carito Guziolowski, Michel Le Borgne, Ovidiu Radulescu, Anne Siegel BMC Bioinformatics 2008, 9 :228 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Distribution of the FY*BES and RHCE*ce(733C>G) alleles in an Argentinean population: implications for transfusion medicine Carlos M Cotorruelo, Silvana V Fiori, Silvia E Garcia Borras, Liliana L Racca, Claudia S Biondi, Amelia L Racca BMC Medical Genetics 2008, 9 :40 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans Erica D Smith, Tammi L Kaeberlein, Brynn T Lydum, Jennifer Sager, K. Linnea Welton, Brian K Kennedy, Matt Kaeberlein BMC Developmental Biology 2008, 8 :49 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Rapid regulation of protein activity in fission yeast Cathrine A Boe, Ignacio Garcia, Chen-Chun Pai, Jeffrey R Sharom, Henriette C Skjolberg, Erik Boye, Stephen Kearsey, Stuart A MacNeill, Michael D Tyers, Beata Grallert BMC Cell Biology 2008, 9 :23 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Expression of HER-2 in MCF-7 breast cancer cells modulates anti-apoptotic proteins Survivin and Bcl-2 via the extracellular signal-related kinase (ERK) and phosphoinositide-3 kinase (PI3K) signalling pathways. Aisha Siddiqa, Linda M Long, Liuxia Li, Robert A Marciniak, Irene Kazhdan BMC Cancer 2008, 8 :129 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
The pairwise disconnectivity index as a new metric for the topological analysis of regulatory networks Anatolij P. Potapov, Bjorn Goemann, Edgar Wingender BMC Bioinformatics 2008, 9 :227 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Molecular discrimination of responders and non-responders to anti-TNF-alpha therapy in rheumatoid arthritis by etanercept Dirk Koczan, Susanne Drynda, Michael Hecker, Andreas Drynda, Reinhard Guthke, Joern Kekow, Hans-Juergen Thiesen Arthritis Research & Therapy 2008, 10 :R50 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Quantitative correlation between promoter methylation and messenger RNA levels of the reduced folate carrier Rui Yang, Wei-Wei Li, Bang H. Hoang, Hansoo Kim, Debabrata Banerjee, Albert Kheradpour, John H. Healey, Paul A Meyers, Joseph R. Bertino, Richard Gorlick BMC Cancer 2008, 8 :124 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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