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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good PhD
Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of chromatin, replication, recombination, mutation, repair, transcription, translation and RNA processing and function.
BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Thomson Reuters (ISI) and Google Scholar.
BMC Molecular Biology 2009, 10 :103
A putative regulatory sequence has been characterized within exon 6A of the vascular endothelial growth factor (VEGF) mRNA, which is involved in alternative splicing of this exon and regulates the expression levels of the isoforms of VEGF.
BMC Molecular Biology 2009, 10 :101
The hypoxia-tolerant grass carp has two CITED3 genes whose promoters bind HIF-1 as they are induced by hypoxia in the liver and kidneys, and whose products are co-transcriptional regulators that interact with p300 and affect HIF-1 activity.
BMC Molecular Biology 2009, 10 :89
Monomers of the transcriptional regulator C-terminal binding protein 2 (CtBP2) bind competitively to the PLDLS-motif cofactor zinc-finger E-box binding homeobox (ZEB) and the histone deacetylase HDAC2, but do not mediate transcriptional repression, while dimers which bind both are functional.
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Research article
Identification of an exonic splicing silencer in exon 6A of the human VEGF gene Rui Wang, Ronald G. Crystal, Neil R. Hackett BMC Molecular Biology 2009, 10 :103 (17 [Abstract ] [Provisional PDF ]
Research article
The sterol carrier protein 2/3-oxoacyl-CoA thiolase (SCPx) is involved in cholesterol uptake in the midgut of Spodoptera litura : gene cloning, expression, localization and functional analyses Xing-Rong Guo, Si-Chun Zheng, Lin Liu, Qi-Li Feng BMC Molecular Biology 2009, 10 :102 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Functional characterization of two CITED3 homologs (gcCITED3a and gcCITED3b) in the hypoxia-tolerant grass carp, Ctenopharyngodon idellus Patrick KS Ng, Sung-Kay Chiu, Theresa FN Kwong, Richard MK Yu, Minnie ML Wong, Richard YC Kong BMC Molecular Biology 2009, 10 :101 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Evaluation of real-time PCR endogenous control genes for analysis of gene expression in bovine endometrium Caroline G Walker, Susanne Meier, Murray D Mitchell, John R Roche, Mathew Littlejohn BMC Molecular Biology 2009, 10 :100 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae Marie-Ange Teste, Manon Duquenne, Jean M Fran BMC Molecular Biology 2009, 10 :99 (30 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions Ellen C Ordinario, Munehisa Yabuki, Priya Handa, W Jason Cummings, Nancy Maizels BMC Molecular Biology 2009, 10 :98 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Preliminary molecular characterization of the human pathogen Angiostrongylus cantonensis Hualiang He, Mei Cheng, Xiao Yang, Jinxiu Meng, Ai He, Xiaoying Zheng, Zhuoya Li, Pengjuan Guo, Zhihua Pan, Ximei Zhan BMC Molecular Biology 2009, 10 :97 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Dual effect of a single nucleotide polymorphism in the first intron of the porcine Secreted phosphoprotein 1 gene: allele-specific binding of C/EBP beta and activation of aberrant splicing Eduard Mur BMC Molecular Biology 2009, 10 :96 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A small intergenic region drives exclusive tissue-specific expression of the adjacent genes in Arabidopsis thaliana Hern BMC Molecular Biology 2009, 10 :95 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Validation of suitable house keeping genes for hypoxia-cultured human chondrocytes Casper Bindzus Foldager, Samir Munir, Michael Ulrik-Vinther, Kjeld S BMC Molecular Biology 2009, 10 :94 (9 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
High-level HIV-1 Nef transient expression in Nicotiana benthamiana using the P19 gene silencing suppressor protein of Artichoke Mottled Crinckle Virus Raffaele Lombardi, Patrizia Circelli, Maria Elena Villani, Giampaolo Buriani, Luca Nardi, Valentina Coppola, Linda Bianco, Eugenio Benvenuto, Marcello Donini, Carla Marusic BMC Biotechnology 2009, 9 :96 (20 [Abstract ] [Provisional PDF ]
Method
COMIT: Identification of noncoding motifs under selection in coding sequences Deniz Kural, Yang Ding, Jiantao Wu, Alicia Korpi, Jeffrey H Chuang Genome Biology 2009, 10 :R133 (20 [Abstract ] [Provisional PDF ]
Research article
The expression of Gli3, regulated by HOXD13, may play a role in idiopathic congenital talipes equinovarus DongHua Cao, ChunLian Jin, MeiHong Ren, ChangKun Lin, Xuan Zhang, Ning Zhao BMC Musculoskeletal Disorders 2009, 10 :142 (19 [Abstract ] [Provisional PDF ]
Research
CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription Hiroshi Hosoda, Kenichi Kato, Hidenori Asano, Motonori Ito, Haruno Kato, Taku Iwamoto, Akinobu Suzuki, Shoichi Masusige, Satoshi Kida Molecular Brain 2009, 2 :34 (19 [Abstract ] [Provisional PDF ]
Research
Evidence of recombination in Hepatitis C Virus populations infecting a hemophiliac patient Pilar Moreno, Macarena Alvarez, Lilia Lopez, Gonzalo Moratorio, Didier Casane, Matias Castells, Silvia Castro, Juan Cristina, Rodney Colina Virology Journal 2009, 6 :203 (18 [Abstract ] [Provisional PDF ]
Research article
Genome scale transcriptome analysis of shoot organogenesis in Populus Yanghuan Bao, Palitha Dharmawardhana, Todd C. Mockler, Steven H. Strauss BMC Plant Biology 2009, 9 :132 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Endothelial cells influence the osteogenic potential of bone marrow stromal cells Ying Xue, Zhe Xing, Solve Hellem, Kristina Arvidson, Kamal Mustafa BioMedical Engineering OnLine 2009, 8 :34 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Expression and function of hypoxia inducible factor-1 alpha in human melanoma under non-hypoxic conditions Caroline N Mills, Sandeep S Joshi, Richard M Niles Molecular Cancer 2009, 8 :104 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Expression profiling of repetitive elements by melting temperature analysis: variation in HERV-W gag expression across human individuals and tissues Christoffer Nell BMC Genomics 2009, 10 :532 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq Mehdi Motallebipour, Adam Ameur, Madhu Sudhan Reddy Bysani, Kalicharan Patra, Ola Wallerman, Jonathan Mangion, Melissa A Barker, Kevin J McKernan, Jan Komorowski, Claes Wadelius Genome Biology 2009, 10 :R129 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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