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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good PhD
Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of chromatin, replication, recombination, mutation, repair, transcription, translation and RNA processing and function.
BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Thomson Reuters (ISI) and Google Scholar.
BMC Molecular Biology 2009, 10 :103
A putative regulatory sequence has been characterized within exon 6A of the vascular endothelial growth factor (VEGF) mRNA, which is involved in alternative splicing of this exon and regulates the expression levels of the isoforms of VEGF.
BMC Molecular Biology 2009, 10 :101
The hypoxia-tolerant grass carp has two CITED3 genes whose promoters bind HIF-1 as they are induced by hypoxia in the liver and kidneys, and whose products are co-transcriptional regulators that interact with p300 and affect HIF-1 activity.
BMC Molecular Biology 2009, 10 :89
Monomers of the transcriptional regulator C-terminal binding protein 2 (CtBP2) bind competitively to the PLDLS-motif cofactor zinc-finger E-box binding homeobox (ZEB) and the histone deacetylase HDAC2, but do not mediate transcriptional repression, while dimers which bind both are functional.
Latest articles published in BMC Molecular Biology [more info ]
Research article
Identification of an exonic splicing silencer in exon 6A of the human VEGF gene Rui Wang, Ronald G. Crystal, Neil R. Hackett BMC Molecular Biology 2009, 10 :103 (17 November 2009) [Abstract ] [Provisional PDF ]
Research article
The sterol carrier protein 2/3-oxoacyl-CoA thiolase (SCPx) is involved in cholesterol uptake in the midgut of Spodoptera litura : gene cloning, expression, localization and functional analyses Xing-Rong Guo, Si-Chun Zheng, Lin Liu, Qi-Li Feng BMC Molecular Biology 2009, 10 :102 (13 November 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Functional characterization of two CITED3 homologs (gcCITED3a and gcCITED3b) in the hypoxia-tolerant grass carp, Ctenopharyngodon idellus Patrick KS Ng, Sung-Kay Chiu, Theresa FN Kwong, Richard MK Yu, Minnie ML Wong, Richard YC Kong BMC Molecular Biology 2009, 10 :101 (3 November 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Evaluation of real-time PCR endogenous control genes for analysis of gene expression in bovine endometrium Caroline G Walker, Susanne Meier, Murray D Mitchell, John R Roche, Mathew Littlejohn BMC Molecular Biology 2009, 10 :100 (1 November 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae Marie-Ange Teste, Manon Duquenne, Jean M Fran ois, Jean-Luc Parrou BMC Molecular Biology 2009, 10 :99 (30 October 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions Ellen C Ordinario, Munehisa Yabuki, Priya Handa, W Jason Cummings, Nancy Maizels BMC Molecular Biology 2009, 10 :98 (28 October 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Preliminary molecular characterization of the human pathogen Angiostrongylus cantonensis Hualiang He, Mei Cheng, Xiao Yang, Jinxiu Meng, Ai He, Xiaoying Zheng, Zhuoya Li, Pengjuan Guo, Zhihua Pan, Ximei Zhan BMC Molecular Biology 2009, 10 :97 (25 October 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Dual effect of a single nucleotide polymorphism in the first intron of the porcine Secreted phosphoprotein 1 gene: allele-specific binding of C/EBP beta and activation of aberrant splicing Eduard Mur ni, Siriluck Ponsuksili, Hans-Martin Seyfert, Xuanming Shi, Klaus Wimmers BMC Molecular Biology 2009, 10 :96 (21 October 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A small intergenic region drives exclusive tissue-specific expression of the adjacent genes in Arabidopsis thaliana Hern n G Bondino, Estela M Valle BMC Molecular Biology 2009, 10 :95 (16 October 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Validation of suitable house keeping genes for hypoxia-cultured human chondrocytes Casper Bindzus Foldager, Samir Munir, Michael Ulrik-Vinther, Kjeld S balle, Cody B nger, Martin Lind BMC Molecular Biology 2009, 10 :94 (9 October 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription Hiroshi Hosoda, Kenichi Kato, Hidenori Asano, Motonori Ito, Haruno Kato, Taku Iwamoto, Akinobu Suzuki, Shoichi Masusige, Satoshi Kida Molecular Brain 2009, 2 :34 (19 November 2009) [Abstract ] [Provisional PDF ]
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Genome scale transcriptome analysis of shoot organogenesis in Populus Yanghuan Bao, Palitha Dharmawardhana, Todd C. Mockler, Steven H. Strauss BMC Plant Biology 2009, 9 :132 (17 November 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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