Emodin targets the β-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization
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* Corresponding authors: Yuewei Guo ywguo@mail.shcnc.ac.cn - Xu Shen xshen@mail.shcnc.ac.cn
- Equal contributors
1 Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, PR China
2 Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, PR China
BMC Microbiology 2009, 9:91 doi:10.1186/1471-2180-9-91
Published: 12 May 2009Additional files
Additional file 1:
Supplemental Materials. Supplemental Figure Legends.
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Additional file 2:
Supplemental Figure S1. pH profile of HpFabZ enzyme activity.
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Additional file 3:
Supplemental Figure S2. The effect of DMSO on HpFabZ enzyme activity.
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