Intracellular replication leads to extrusion of C. neoformans phagosome. HPBMs were incubated with C. neoformans strain H99. Following incubation, C. neoformans budding occurred every 2–3 hours as evidenced by the small arrows. This was followed by extrusion of the C. neoformans phagosomes as evidenced by the large arrow. Images were collected at 10×.
Alvarez et al. BMC Microbiology 2009 9:51 doi:10.1186/1471-2180-9-51