The outcome of Cryptococcus neoformans intracellular pathogenesis in human monocytes
Department of Microbiology and Immunology and Medicine, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, NY 10461, USA
BMC Microbiology 2009, 9:51 doi:10.1186/1471-2180-9-51Published: 5 March 2009
Replication of C. neoformans within human peripheral blood monocytes. The data provided represents intracellular replication of C. neoformans in HPBM cells at rates similar to extracellular C. neoformans (every 2 to 3 h).
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Cell to cell spread of C. neoformans in human peripheral blood monocytes. Cell to cell spread was witnessed following ingestion and subsequent imaging of infected HPBMs, we witnessed that C. neoformans also spread from host human monocyte to another uninfected one.
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