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Analytical sensitivity of Candida cells capture with IMS method |
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| Strains |
Time (hours) of positive blood culture (mean ± SD)a |
CFU/ml in initial contaminated blood |
CFU/ml after IMS (mean ± SD)a |
Immunocaptured cells (% ± SD)ab |
|
|
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| Candida albicans 5575 |
25.45 ± 0.59 |
32 |
8.8 ± 0.6 |
27.5 ± 1.9 |
| Candida albicans ATCC 66396 |
25.95 ± 1.46 |
6 |
1.75 ± 0.3 |
29.1 ± 3.8 |
| Candida krusei 5374 |
22.26 ± 0.48 |
30 |
3.25 ± 0.5 |
10.8 ± 1.7 |
| Candida krusei 5481 |
16.20 ± 0.28 |
40 |
17.3 ± 2.5 |
43.2 ± 6.2 |
| Candida glabrata 5511 |
25.05 ± 0.5 |
20 |
7.6 ± 1.3 |
38 ± 6.4 |
| Candida glabrata 5484 |
25.38 ± 0.58 |
10 |
3.8 ± 0.6 |
38 ± 6.3 |
| Candida tropicalis 5437 |
19.02 ± 0.88 |
30 |
4.8 ± 2.2 |
16 ± 3.8 |
| Candida tropicalis 5395 |
17.51 ± 0.50 |
30 |
4.3 ± 2.2 |
14.3 ± 7.3 |
|
acalculation of mean and SD is derived from three different experiments bpercentage of immunocaptured cells: number of CFU per 1 ml of blood after IMS procedure/number of CFU per 1 ml of blood in initial contaminated blood CFU: Colony Forming Unit, IMS : ImmunoMagnetic Separation, SD : Standard Deviation | ||||
Apaire-Marchais et al. BMC Microbiology 2008 8:157 doi:10.1186/1471-2180-8-157 |
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