Table 2

Changes in M. pneumoniae lipoprotein gene expression after contact with human A549 cells for 2 hours, or after incubation in 20 mM H2O2 or at pH 5.5 for 10 min

Lipoprotein family
Gene annotation (NCBI)
Change in expression (fold) after:





Contact with A549 cells#
P value
20 mM H2O2 for 10 min†
P value
pH 5.5 for 10 min§
P value

1
MPN084
1.1
0.714
0.5
0.439
1
0.910

MPN591
1
0.966
0.8
0.645
1.6
0.275

MPN592
0.9
0.880
0.9
0.906
0.9
0.825

MPN083
1
0.934
1.7
0.504
1.3
0.605

MPN588
1.9
0.002**
0.6
0.475
0.8
0.504

MPN582
1.2
0.586
0.4
0.375
0.6
0.222








2
MPN199
2.5
0.003**
0.6
0.443
0.6
0.220

MPN408
0.8
0.469
0.4
0.105
0.2
0.001**

MPN200
3.3
0.006**
0.4
0.195
0.4
0.037*

MPN152
1.2
0.677
0.2
0.104
0.2
0.020*








3
MPN436
0.9
0.802
0.4
0.094
0.9
0.836

MPN444
1.3
0.549
0.7
0.240
0.8
0.555

MPN489
1.4
0.286
0.6
0.033*
0.7
0.328








4
MPN456
2.2
0.010*
0.8
0.681
0.5
0.082








5
MPN011
1.6
0.044*
0.4
0.299
0.6
0.316

MPN012
1.5
0.119
0.3
0.122
0.6
0.257

MPN411
1.9
0.032*
0.5
0.345
0.7
0.442

MPN271
1.2
0.638
0.6
0.451
0.9
0.794

MPN505
0.8
0.602
0.3
0.095
1.5
0.302








6
MPN647
1.2
0.603
0.4
0.130
2.3
0.081

MPN646
0.9
0.846
0.5
0.097
1.8
0.177

MPN645
1.4
0.360
0.5
0.624
1.3
0.398

MPN644
1.1
0.876
0.6
0.358
0.9
0.753

MPN643
1.5
0.208
0.6
0.503
1.1
0.831

MPN642
1.1
0.895
0.6
0.323
0.7
0.457

MPN641
1.7
0.208
0.5
0.063
0.6
0.264

MPN640
1
0.980
0.6
0.431
0.9
0.658

MPN639
1.1
0.766
0.3
0.007**
0.8
0.514

* P value < 0.05.

** P value < 0.01.

# Mean of three independent experiments, each containing three biological replicates.

† Mean of four independent experiments.

§ Mean of three independent experiments.

Hallamaa et al. BMC Microbiology 2008 8:124   doi:10.1186/1471-2180-8-124