|
Changes in M. pneumoniae lipoprotein gene expression after contact with human A549 cells for 2 hours, or after incubation in 20 mM H2O2 or at pH 5.5 for 10 min |
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| Lipoprotein family |
Gene annotation (NCBI) |
Change in expression (fold) after: |
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|
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| Contact with A549 cells# |
P value |
20 mM H2O2 for 10 min† |
P value |
pH 5.5 for 10 min§ |
P value |
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|
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| 1 |
MPN084 |
1.1 |
0.714 |
0.5 |
0.439 |
1 |
0.910 |
| MPN591 |
1 |
0.966 |
0.8 |
0.645 |
1.6 |
0.275 |
|
| MPN592 |
0.9 |
0.880 |
0.9 |
0.906 |
0.9 |
0.825 |
|
| MPN083 |
1 |
0.934 |
1.7 |
0.504 |
1.3 |
0.605 |
|
| MPN588 |
1.9 |
0.002** |
0.6 |
0.475 |
0.8 |
0.504 |
|
| MPN582 |
1.2 |
0.586 |
0.4 |
0.375 |
0.6 |
0.222 |
|
| 2 |
MPN199 |
2.5 |
0.003** |
0.6 |
0.443 |
0.6 |
0.220 |
| MPN408 |
0.8 |
0.469 |
0.4 |
0.105 |
0.2 |
0.001** |
|
| MPN200 |
3.3 |
0.006** |
0.4 |
0.195 |
0.4 |
0.037* |
|
| MPN152 |
1.2 |
0.677 |
0.2 |
0.104 |
0.2 |
0.020* |
|
| 3 |
MPN436 |
0.9 |
0.802 |
0.4 |
0.094 |
0.9 |
0.836 |
| MPN444 |
1.3 |
0.549 |
0.7 |
0.240 |
0.8 |
0.555 |
|
| MPN489 |
1.4 |
0.286 |
0.6 |
0.033* |
0.7 |
0.328 |
|
| 4 |
MPN456 |
2.2 |
0.010* |
0.8 |
0.681 |
0.5 |
0.082 |
| 5 |
MPN011 |
1.6 |
0.044* |
0.4 |
0.299 |
0.6 |
0.316 |
| MPN012 |
1.5 |
0.119 |
0.3 |
0.122 |
0.6 |
0.257 |
|
| MPN411 |
1.9 |
0.032* |
0.5 |
0.345 |
0.7 |
0.442 |
|
| MPN271 |
1.2 |
0.638 |
0.6 |
0.451 |
0.9 |
0.794 |
|
| MPN505 |
0.8 |
0.602 |
0.3 |
0.095 |
1.5 |
0.302 |
|
| 6 |
MPN647 |
1.2 |
0.603 |
0.4 |
0.130 |
2.3 |
0.081 |
| MPN646 |
0.9 |
0.846 |
0.5 |
0.097 |
1.8 |
0.177 |
|
| MPN645 |
1.4 |
0.360 |
0.5 |
0.624 |
1.3 |
0.398 |
|
| MPN644 |
1.1 |
0.876 |
0.6 |
0.358 |
0.9 |
0.753 |
|
| MPN643 |
1.5 |
0.208 |
0.6 |
0.503 |
1.1 |
0.831 |
|
| MPN642 |
1.1 |
0.895 |
0.6 |
0.323 |
0.7 |
0.457 |
|
| MPN641 |
1.7 |
0.208 |
0.5 |
0.063 |
0.6 |
0.264 |
|
| MPN640 |
1 |
0.980 |
0.6 |
0.431 |
0.9 |
0.658 |
|
| MPN639 |
1.1 |
0.766 |
0.3 |
0.007** |
0.8 |
0.514 |
|
|
* P value < 0.05. ** P value < 0.01. # Mean of three independent experiments, each containing three biological replicates. † Mean of four independent experiments. § Mean of three independent experiments. | |||||||
Hallamaa et al. BMC Microbiology 2008 8:124 doi:10.1186/1471-2180-8-124 |
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