Table 2

List of selected up- and down- regulated genes during alkali adaptation.

Locus ID
Symbol
Fold
P value
Sub-functional category
Gene/protein name

lmo2673
NA
5.38
0.000
Adaptations to atypical conditions
Conserved hypothetical protein
lmo1074
NA
-3.92
0.007
Amino acids, peptides and amines
Highly similar to teichoic acid translocation permease protein TagG
lmo2250
arpJ
-3.65
0.007

Similar to amino acid ABC transporter, permease protein
lmo0847
NA
-3.34
0.008

Similar to glutamine ABC transporter (binding and transport protein)
lmo0997
clpE
3.64
0.013

ATP-dependent protease
LMOf2365_2469
NA
3.44
0.025
Anions
Phosphate ABC transporter, ATP-binding protein
LMOf2365_2470
NA
4.19
0.002

Phosphate ABC transporter, permease protein
lmo2495
NA
6.03
0.000

Similar to phosphate ABC transporter
LMOf6854_2559
NA
8.01
0.000

Phosphate ABC transporter, permease protein
lmo0097
NA
-6.17
0.004
Aromatic amino acid family
Similar to PTS system mannose-specific, factor IIC
lmo2202
NA
-3.61
0.001
Biosynthesis
Similar to 3-oxoacyl- acyl-carrier protein synthase
LMOf2365_2674
NA
3.18
0.055

Putative Dihydroxyacetone kinase, Dak1 subunit
LMOf6854_2815
NA
5.21
0.000

Dihydroxyacetone kinase, Dak2 subunit, putative
LMOf6854_2814
NA
5.79
0.000

Dihydroxyacetone kinase, Dak1 subunit, putative
lmo1389
NA
-4.31
0.006
Carbohydrates, organic alcohols & acids
Similar to sugar ABC transporter, ATP-binding protein
LMOf2365_1877
NA
-7.45
0.003
Cations and iron carrying compounds
Manganese ABC transporter, ATP-binding protein
lmo1848
NA
-6.13
0.003

Similar metal cations ABC transporter
lmo2087
NA
4.03
0.004

Similar to unknown proteins
lmo2507
ftsE
-4.06
0.002
Cell division
Highly similar to cell-division ATP-binding protein FtsE
lmo0582
iap
-3.9
0.004

P60 extra cellular protein, invasion associated protein iap
lmo1603
NA
-5.43
0.006
Degradation of proteins, peptides, and glycopeptides
Similar to aminopeptidase
lmo2230
NA
5.04
0.000
Detoxification
Similar to arsenate reductase
LMOf2365_2669
NA
3.22
0.048
DNA interactions
Transcriptional regulator, TetR family
lmo1398
recA
3.12
0.001
DNA replication, recombination, and repair
Recombination protein recA
lmo2489
uvrB
3.42
0.026

Excinuclease ABC (subunit B)
lmo2676
NA
3.48
0.022

Similar to UV-damage repair protein
lmo2717
cydB
-3.3
0.004
Electron transport
Highly similar to cytochrome D ubiquinol oxidase subunit II
lmo1067
NA
-4.37
0.005
General
Similar to GTP-binding elongation factor
lmo2494
NA
5.35
0.001
Glycolysis/gluconeogenesis
Similar to negative regulator of phosphate regulon
lmo0786
NA
-4.02
0.001
Other
Similar to acyl-carrier phosphodiesterase and to NAD(P)H dehydrogenase
lmo1870
NA
4.22
0.002

Similar to alkali phosphatase
lmo0820
NA
4.7
0.000

Some similarity to acatyltransferases
lmo1974
NA
5.12
0.001

Similar to transcription regulators, (GntR family)
LMOh7858_0838
NA
3.24
0.104
PTS
PTS system, mannose/fructose/sorbose family, IIA component subfamily
lmo2632
rplC
-3.44
0.003
Ribosomal proteins : synthesis and modification
Ribosomal protein L3
lmo0250
rplJ
-3.36
0.004

Ribosomal protein L10
lmo2631
rplD
-3.26
0.004

Ribosomal protein L4
lmo1252
NA
5.69
0.001
Role category not yet assigned
Similar to B. subtilis YxkD protein
lmo2695
NA
4.55
0.001
Sugars
Similar to dihydroxyacetone kinase

Giotis et al. BMC Microbiology 2008 8:102   doi:10.1186/1471-2180-8-102