Table 2

Description of the M. tuberculosis clusters found in Venezuela.

1SIT
Spoligotyping patterns -Binary description
2n
%
3Clade
4C-1

17

122
21.94
LAM-2
Ubiquitous
42

86
15.47
LAM-9
Ubiquitous
93

70
12.59
LAM-5
Ubiquitous
53

26
4.6S
T-1
Ubiquitous
20

26
4.63
LAM-1
Ubiquitous
605

18
3.24
U
Loc (VEN/USA)
1691

14
2.52
LAM-2
Endemic (VEN)
60

13
2.39
LAM-4
Ubiquitous
905

10
1.60
U
Loc (VEN-USA-ARG)
118

9
1.61
T-2
Ubiquitous
50

9
1.61
H-3
Ubiquitous
51

8
1.43
T-1
Ubiquitous
333

7
1.25
LAM-5
Loc (GUP-GUF-HTI-VEN)
960

5
0.90
U
Loc (VEN-USA)
34

5
0.90
S
Ubiquitous
194

5
0.90
LAM-4
Loc (USA-BRA-MEX-VEN)
1696

5
0.90
LAM-5
Endemic (VEN)
47

5
0.90
H-1
Ubiquitous
130

4
0.71
LAM-3
Ubiquitous
150

4
0.71
LAM-9
Ubiquitous
397

4
0.71
U
Loc (ITA-BRA-ARG-USA-VEN)
1692

4
0.71
U
Endemic (VEN)
1700

4
0.71
T-1
Endemic (VEN)
33

3
0.54
LAM-3
Ubiquitous
44

3
0.54
T-4
Ubiquitous
58

3
0.54
T-5
Ubiquitous
64

3
0.54
LAM-6
Ubiquitous
162

3
0.54
U
Loc (ARG-VEN-USA-FIN-FXX-ITA)
376

3
0.54
LAM-3
Loc (VEN-USA)
578

3
0.54
LAM-9
Loc (USA-VEN)
1698

3
0.54
U
Endemic (VEN)
1701

3
0.54
LAM-9
Endemic (VEN)
1702

3
0.54
LAM-5
Endemic (VEN)
1705

3
0.54
T-1
Endemic (VEN)
1713

3
0.54
LAM-1
Endemic (VEN)
1718

3
0.54
LAM-9
Endemic (VEN)
52

2
0.36
T-2
Ubiquitous
62

2
0.36
H-1
Ubiquitous
71

2
0.36
S
Ubiquitous
106

2
0.36
U
Loc (CUB-ECU-M EX-USA-VEN)
132

2
0.36
U
Loc (ESP-AUS-BRA-VEN)
167

2
0.36
T
Ubiquitous
178

2
0.36
LAM-4
Loc (CUB-SEN-VEN)
196

2
0.36
T-1
Ubiquitous
388

2
0.36
LAM-9
Ubiquitous
389

2
0.36
LAM-1
Loc (BRA-PRT-FIN-VEN)
430

2
0.36
T-4
Loc (USA-VEN)
1166

2
0.36
T-1
Ubiquitous (MWI-USA-VEN)
1661

2
0.36
LAM-2
Loc (VEN-BRA)
1693

2
0.36
LAM-5
Endemic (VEN)
1699

2
0.36
LAM-9
Endemic (VEN)
1703

2
0.36
LAM-9
Endemic (VEN)
1704

2
0.36
LAM-5
Endemic (VEN)
1707

2
0.36
T-1
Endemic (VEN)
1711

2
0.36
LAM-2
Endemic (VEN)
1714

2
0.36
LAM-9
Endemic (VEN)
1715

2
0.36
LAM-4
Endemic (VEN)
1716

2
0.36
T-3
Endemic (VEN)
1719

2
0.36
LAM-2
Endemic (VEN)
1694

1
0.18
LAM-5
Loc (VEN-USA)-Cluster inter-region
1695

1
0.18
LAM-2
Loc (VEN-BRA)-Cluster inter-region
1697

1
0.18
LAM-9
Loc (VEN-FXX)-Cluster inter-region
1706

1
0.18
LAM-9
Loc (VEN-USA)-Cluster inter-region
1708

1
0.18
LAM-9
Loc (VEN-LVA)-Cluster inter-region
1709

1
0.18
LAM-5
Loc (VEN-USA)-Cluster inter-region
1710

1
0.18
LAM-4
Loc (VEN-NLD)-CIuster inter-region
1717

1
0.18
X-1
Loc (VEN-AUS)-Cluster inter-region

Total

556
100



1SIT, designation of the spoligotype in the international database [19]. 2n: Number of strains. 3Clade: defined mainly as described [20, 21] LAM: Latin American and Mediterranean, H: Haarlem, T (ill-defined T clade), S: S clade, X: X clade, U: Undesignated. 4C-1: qualifier that tentatively defines an SIT as Endemic, Loc: localized or ubiquitous, as defined in Filliol et al. [20]. Geographic distribution: VEN: Venezuela, USA: United States of America, BRA: Brazil, GUP: Guadeloupe, GUF: French Guiana, HTI: Haiti, ESP: Spain, ECU: Ecuador, ARG: Argentina, CUB: Cuba, MEX: Mexico, SEN: Senegal, PRT: Portugal, FIN: Finland, ITA: Italy, MWI: Malawi, FXX: Metropolitan France, LVA: Latvia, NLD: The Netherlands, AUS: Australia.

Aristimuño et al. BMC Microbiology 2006 6:90   doi:10.1186/1471-2180-6-90