Figure 1.

Multiple sequence alignment of mutacin H-29B with homologous type AII lantibiotics. Only propeptides are shown. Conserved amino acids are in bold-type. Bacteriocin ruminococcin A is produced by Ruminococcus gnavus [25], butyrivibriocin OR79A by Butyrivibrio fibrisolvens [26], salivaricin A by Streptococcus salivarius [27], lacticin 481 by Lactococcus lactis [28], variacin by Micrococcus varians [29], nukacin ISK-1 by Staphylococcus warneri [30], mutacin II (J-T8) [16], and streptococcin A-M49, A-FF22 and A-FF22' are produced by Streptococcus pyogenes [31, 32].